close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
S100A14S100 calcium binding protein A14; Belongs to the S-100 family. (104 aa)    
Predicted Functional Partners:
GINM1
Glycoprotein integral membrane 1.
      
 0.827
CXorf38
Chromosome X open reading frame 38.
      
 0.825
PJA1
Praja ring finger ubiquitin ligase 1.
      
 0.786
JRKL
JRK like.
      
 0.777
PAQR5
Progestin and adipoQ receptor family member 5.
      
 0.777
S100A5
Protein S100; Belongs to the S-100 family.
      
 0.762
LCTL
Lactase like; Belongs to the glycosyl hydrolase 1 family.
      
 0.742
PIP4K2C
Phosphatidylinositol-5-phosphate 4-kinase type 2 gamma.
      
 0.735
MID1IP1
MID1 interacting protein 1.
      
 0.696
S100A4
Protein S100; Belongs to the S-100 family.
   
 
 0.680
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
Server load: low (30%) [HD]