Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PTF1AUncharacterized protein. (85 aa)    
Predicted Functional Partners:
FOXN4
Forkhead box N4.
    
 0.932
BARHL2
BarH like homeobox 2.
      
 0.868
RBPJL
Recombination signal binding protein for immunoglobulin kappa J region like.
   
 0.843
RBPJ
Recombination signal binding protein for immunoglobulin kappa J region.
   
 0.832
CPA1
Carboxypeptidase A1.
   
  
 0.813
SOX9
SRY-box transcription factor 9.
    
 
 0.797
ATOH1
Atonal bHLH transcription factor 1.
   
 
 0.780
VSX1
Visual system homeobox 1.
      
 0.779
NKX6-1
Homeobox domain-containing protein.
      
 0.771
PAX6
Paired box 6.
      
 0.770
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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