STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SYNRGSynergin gamma. (1416 aa)    
Predicted Functional Partners:
ITSN2
Intersectin 2.
   
 0.990
ITSN1
Intersectin 1.
   
 0.916
BLM
BLM RecQ like helicase.
   
  
 0.817
GAK
Cyclin G associated kinase.
   
 0.789
AP1G1
AP-1 complex subunit gamma.
   
 0.747
FBXL5
F-box and leucine rich repeat protein 5.
      
 0.737
SNX14
Sorting nexin 14.
      
 0.734
SH3RF1
RING-type domain-containing protein.
    
 
 0.701
W5Q1T1_SHEEP
Uncharacterized protein.
    
 
 0.701
AP1S2
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
 
 0.669
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.