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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ASIC3Acid sensing ion channel subunit 3; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (411 aa)    
Predicted Functional Partners:
PKD1L3
Polycystin 1 like 3, transient receptor potential channel interacting.
      
 0.739
TRPV1
Transient receptor potential cation channel subfamily V member 1.
      
 0.611
ABLIM3
Actin binding LIM protein family member 3.
      
 0.592
PRSS57
Serine protease 57; Belongs to the peptidase S1 family.
      
 0.587
HIGD2A
HIG1 domain-containing protein.
      
 0.541
KCNQ5
Potassium voltage-gated channel subfamily Q member 5; Belongs to the potassium channel family.
      
 0.512
TRPC4
Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family.
      
 0.506
MILR1
Mast cell immunoglobulin like receptor 1.
      
 0.491
CCM2
CCM2 scaffold protein.
      
 0.488
CDH15
Cadherin 15; Cadherins are calcium-dependent cell adhesion proteins.
      
 0.459
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.