STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DMBX1Diencephalon/mesencephalon homeobox 1. (393 aa)    
Predicted Functional Partners:
SIK3
SIK family kinase 3.
      
 0.812
LURAP1
Leucine rich adaptor protein 1.
      
 0.729
EFCAB14
Uncharacterized protein.
      
 0.700
CCHCR1
Coiled-coil alpha-helical rod protein 1.
   
 
 0.668
CACUL1
CDK2 associated cullin domain 1; Belongs to the cullin family.
      
 0.659
PLAGL2
PLAG1 like zinc finger 2.
   
 
 0.600
MAST2
Microtubule associated serine/threonine kinase 2.
      
 0.570
MKNK1
MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily.
      
 0.570
NSUN4
NOP2/Sun RNA methyltransferase 4; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
    
 
 0.523
ZNF436
Zinc finger protein 436.
   
 
 0.493
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.