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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CILP2Ig-like domain-containing protein. (587 aa)    
Predicted Functional Partners:
FITM1
Fat storage inducing transmembrane protein 1.
      
 0.828
VWA5A
Von Willebrand factor A domain containing 5A.
      
 0.772
MTBP
MDM2 binding protein.
      
 0.762
MRPL55
Mitochondrial ribosomal protein L55.
      
 0.685
SCLY
Selenocysteine lyase.
      
 0.682
SGTA
Small glutamine rich tetratricopeptide repeat containing alpha.
      
 0.668
ERLIN2
ER lipid raft associated 2.
      
 0.653
RFXANK
Regulatory factor X associated ankyrin containing protein.
      
 0.606
RAB6B
RAB6B, member RAS oncogene family.
      
 0.597
COX15
Cytochrome c oxidase assembly homolog COX15.
      
 0.590
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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