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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5NX42_SHEEPHeparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. (242 aa)    
Predicted Functional Partners:
GLCE
Glucuronic acid epimerase.
    
 
 0.650
HS3ST1
Sulfotransferase; Belongs to the sulfotransferase 1 family.
      
 0.613
HS3ST5
Sulfotransferase; Belongs to the sulfotransferase 1 family.
      
 0.603
NDST4
N-deacetylase and N-sulfotransferase 4.
      
 0.595
NDST3
N-deacetylase and N-sulfotransferase 3.
      
 0.584
HS6ST2
Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
  
   
0.576
ARMC12
Armadillo repeat containing 12.
      
 0.569
HS2ST1
Uncharacterized protein.
    
 
 0.553
SULF2
Sulfatase 2.
    
 
 0.548
WDR64
WD repeat domain 64.
      
 0.538
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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