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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CLEC4GC-type lectin domain family 4 member G. (292 aa)    
Predicted Functional Partners:
W5NWC0_SHEEP
Uncharacterized protein.
     
 0.666
PET100
PET100 cytochrome c oxidase chaperone.
      
 0.662
CLEC1B
C-type lectin domain family 1 member B.
   
  
 0.622
PGLYRP2
Peptidoglycan recognition protein 2.
      
 0.603
SUSD4
Sushi domain containing 4.
      
 0.598
GCSAM
Germinal center associated signaling and motility.
      
 0.591
PCP2
Purkinje cell protein 2.
      
 0.582
CEP295
Centrosomal protein 295.
    
 
 0.546
MORC1
MORC family CW-type zinc finger 1.
   
  
 0.545
CEP295NL
Uncharacterized protein.
      
 0.535
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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