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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5NX73_SHEEPUncharacterized protein. (327 aa)    
Predicted Functional Partners:
ATPAF2
ATP synthase mitochondrial F1 complex assembly factor 2.
   
 
 0.658
ATP5F1B
ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.
    
 
 0.485
TSPAN6
Tetraspanin.
      
 0.481
KIRREL2
Kirre like nephrin family adhesion molecule 2.
      
 0.481
CCDC15
Coiled-coil domain containing 15.
      
 0.481
RGS14
Regulator of G protein signaling 14.
      
 0.480
ALDH7A1
Aldehyde dehydrogenase 7 family member A1; Belongs to the aldehyde dehydrogenase family.
      
 0.480
GPR68
G protein-coupled receptor 68; Belongs to the G-protein coupled receptor 1 family.
      
 0.478
CDCA8
Cell division cycle associated 8.
    
 
 0.430
NDUFAB1
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
   
  
 0.400
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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