STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHOX2Short stature homeobox 2. (315 aa)    
Predicted Functional Partners:
W5NWZ4_SHEEP
Uncharacterized protein.
      
 0.646
TBX18
T-box transcription factor 18.
   
 
 0.636
BOLA1
BolA family member 1; Belongs to the BolA/IbaG family.
      
 0.580
HCN4
Cyclic nucleotide-binding domain-containing protein.
      
 0.549
W5QCC7_SHEEP
Uncharacterized protein.
    
 
 0.544
BANP
BTG3 associated nuclear protein.
    
 
 0.540
ANKRD42
ANK_REP_REGION domain-containing protein.
      
 0.489
TBX5
T-box transcription factor 5.
    
 
 0.464
EIF2B3
Eukaryotic translation initiation factor 2B subunit gamma.
      
 0.442
SCN5A
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
    
 0.438
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
Server load: low (26%) [HD]