STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CBX4Chromobox 4. (510 aa)    
Predicted Functional Partners:
BMI1
RING-type domain-containing protein.
    
 0.989
RING1
Ring finger protein 1.
    
 0.986
CBX8
Chromobox 8.
    
0.973
RNF2
Ring finger protein 2.
    
 0.971
PCGF2
Polycomb group ring finger 2.
    
 0.964
CBX2
Chromobox 2.
  
 
0.956
PHC3
Polyhomeotic homolog 3.
    
 0.944
YAF2
YY1 associated factor 2.
    
 0.896
PHC1
Polyhomeotic homolog 1.
    
 0.889
PHC2
Polyhomeotic homolog 2.
    
 0.889
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.