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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CES4ACarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (560 aa)    
Predicted Functional Partners:
LRIT1
Leucine rich repeat, Ig-like and transmembrane domains 1.
    
 0.761
CLDND1
Claudin domain containing 1.
      
 0.730
GPR182
G protein-coupled receptor 182; Belongs to the G-protein coupled receptor 1 family.
      
 0.727
CYTH4
Cytohesin 4.
   
  
 0.645
GABPA
GA binding protein transcription factor subunit alpha.
      
 0.590
W5Q0Y7_SHEEP
Uncharacterized protein.
      
 0.577
SP4
Sp4 transcription factor.
   
 0.540
VARS2
Valyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family.
      
 0.538
COL25A1
Collagen type XXV alpha 1 chain.
    
 
 0.526
OXSM
3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
      
 0.520
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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