STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NYXNyctalopin. (347 aa)    
Predicted Functional Partners:
TRPM1
Transient receptor potential cation channel subfamily M member 1.
      
 0.942
CACNA1F
Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
     
 0.878
AP5B1
Adaptor related protein complex 5 subunit beta 1.
    
 0.837
GNB3
G protein subunit beta 3.
     
 0.787
RGS7
Regulator of G protein signaling 7.
      
 0.761
GRM6
Glutamate metabotropic receptor 6.
     
 0.737
RGS11
Regulator of G protein signaling 11.
   
  
 0.735
TAAR5
Trace amine associated receptor 5; Belongs to the G-protein coupled receptor 1 family.
     
 0.727
EGFLAM
EGF like, fibronectin type III and laminin G domains.
   
 0.710
GPR179
G protein-coupled receptor 179.
     
 0.698
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.