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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C16orf70Chromosome 16 open reading frame 70. (422 aa)    
Predicted Functional Partners:
W5Q502_SHEEP
Uncharacterized protein.
   
 
 0.825
BCAS3
BCAS3 microtubule associated cell migration factor.
   
 
 0.825
WDR45
Uncharacterized protein.
   
  
 0.707
ZFYVE1
Zinc finger FYVE-type containing 1.
   
  
 0.696
WDR45B
Uncharacterized protein.
   
  
 0.624
WHAMM
WASP homolog associated with actin, golgi membranes and microtubules.
    
 
 0.624
W5Q4C3_SHEEP
Uncharacterized protein.
   
  
 0.624
JMY
Junction mediating and regulatory protein, p53 cofactor.
    
 
 0.614
ATG2A
Autophagy related 2A.
      
 0.613
LOC101112509
Uncharacterized protein.
      
 0.613
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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