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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5NXG9_SHEEPTNF_2 domain-containing protein. (153 aa)    
Predicted Functional Partners:
LTBR
Lymphotoxin beta receptor.
   
 0.945
W5P8A1_SHEEP
Uncharacterized protein.
   
 0.731
TNFSF13B
TNF superfamily member 13b; Belongs to the tumor necrosis factor family.
   
 
 0.683
TNFSF12
TNF superfamily member 12; Belongs to the tumor necrosis factor family.
   
 
 0.680
CD40
CD40 molecule.
   
 0.679
CD40LG
CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.
     
 0.678
TNFRSF11B
TNF receptor superfamily member 11b.
   
 0.651
TNFSF11
TNF superfamily member 11; Belongs to the tumor necrosis factor family.
     
 0.642
TRAF3
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.611
W5P7X8_SHEEP
TNFR-Cys domain-containing protein.
     
 0.606
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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