close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCAMP5Secretory carrier-associated membrane protein. (265 aa)    
Predicted Functional Partners:
PKNOX2
PBX/knotted 1 homeobox 2.
      
 0.731
CLK3
CDC like kinase 3.
 
    
 0.694
GCM2
Glial cells missing transcription factor 2.
      
 0.658
APBA2
Amyloid beta precursor protein binding family A member 2.
   
  
 0.622
W5NT75_SHEEP
Uncharacterized protein.
      
 0.612
ADPGK
ADP dependent glucokinase.
      
 0.586
KLC2
Kinesin light chain 2.
      
 0.579
EFHC2
EF-hand domain containing 2.
      
 0.567
NEO1
Neogenin 1.
      
 0.566
KIAA0408
KIAA0408.
      
 0.565
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.