node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACE2 | AGT | ENSOARP00000013345 | ENSOARP00000003247 | Angiotensin-converting enzyme. | Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. Belongs to the serpin family. | 0.991 |
ACE2 | MAS1 | ENSOARP00000013345 | ENSOARP00000002953 | Angiotensin-converting enzyme. | MAS1 proto-oncogene, G protein-coupled receptor; Belongs to the G-protein coupled receptor 1 family. | 0.632 |
ACE2 | MME | ENSOARP00000013345 | ENSOARP00000003611 | Angiotensin-converting enzyme. | Membrane metalloendopeptidase. | 0.993 |
ACE2 | REN | ENSOARP00000013345 | ENSOARP00000002426 | Angiotensin-converting enzyme. | Renin; Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. | 0.984 |
AGT | ACE2 | ENSOARP00000003247 | ENSOARP00000013345 | Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. Belongs to the serpin family. | Angiotensin-converting enzyme. | 0.991 |
AGT | MAS1 | ENSOARP00000003247 | ENSOARP00000002953 | Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. Belongs to the serpin family. | MAS1 proto-oncogene, G protein-coupled receptor; Belongs to the G-protein coupled receptor 1 family. | 0.943 |
AGT | MME | ENSOARP00000003247 | ENSOARP00000003611 | Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. Belongs to the serpin family. | Membrane metalloendopeptidase. | 0.919 |
AGT | REN | ENSOARP00000003247 | ENSOARP00000002426 | Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. Belongs to the serpin family. | Renin; Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. | 0.994 |
ASAH1 | MAS1 | ENSOARP00000009348 | ENSOARP00000002953 | N-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family. | MAS1 proto-oncogene, G protein-coupled receptor; Belongs to the G-protein coupled receptor 1 family. | 0.542 |
ASAH1 | SLC44A3 | ENSOARP00000009348 | ENSOARP00000018687 | N-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family. | Solute carrier family 44 member 3; Belongs to the CTL (choline transporter-like) family. | 0.542 |
ASAH1 | UBL7 | ENSOARP00000009348 | ENSOARP00000003973 | N-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family. | Ubiquitin like 7. | 0.551 |
ASAH1 | W5P0J2_SHEEP | ENSOARP00000009348 | ENSOARP00000003940 | N-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family. | Uncharacterized protein. | 0.551 |
CIAPIN1 | MAS1 | ENSOARP00000000187 | ENSOARP00000002953 | Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...] | MAS1 proto-oncogene, G protein-coupled receptor; Belongs to the G-protein coupled receptor 1 family. | 0.722 |
CIAPIN1 | SLC44A3 | ENSOARP00000000187 | ENSOARP00000018687 | Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...] | Solute carrier family 44 member 3; Belongs to the CTL (choline transporter-like) family. | 0.703 |
CIAPIN1 | UBL7 | ENSOARP00000000187 | ENSOARP00000003973 | Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...] | Ubiquitin like 7. | 0.638 |
CIAPIN1 | W5P0J2_SHEEP | ENSOARP00000000187 | ENSOARP00000003940 | Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...] | Uncharacterized protein. | 0.638 |
MAS1 | ACE2 | ENSOARP00000002953 | ENSOARP00000013345 | MAS1 proto-oncogene, G protein-coupled receptor; Belongs to the G-protein coupled receptor 1 family. | Angiotensin-converting enzyme. | 0.632 |
MAS1 | AGT | ENSOARP00000002953 | ENSOARP00000003247 | MAS1 proto-oncogene, G protein-coupled receptor; Belongs to the G-protein coupled receptor 1 family. | Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. Belongs to the serpin family. | 0.943 |
MAS1 | ASAH1 | ENSOARP00000002953 | ENSOARP00000009348 | MAS1 proto-oncogene, G protein-coupled receptor; Belongs to the G-protein coupled receptor 1 family. | N-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family. | 0.542 |
MAS1 | CIAPIN1 | ENSOARP00000002953 | ENSOARP00000000187 | MAS1 proto-oncogene, G protein-coupled receptor; Belongs to the G-protein coupled receptor 1 family. | Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...] | 0.722 |