UBR3 protein (Ovis aries) - STRING interaction network

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UBR3

E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1868 aa)

Predicted Functional Partners:

HECTD1

0.828

NINL

0.822

CUL5

0.808

ARHGAP4

0.710

WDTC1

0.696

USH2A

0.659

CDH23

0.630

SHISA2

0.600

UBR7

0.579

UBR5

0.568

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGAP4	UBR3	ENSOARP00000001579	ENSOARP00000002983	Rho GTPase activating protein 4.	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	0.710
CDH23	NINL	ENSOARP00000007171	ENSOARP00000002658	Cadherin related 23.	Uncharacterized protein.	0.584
CDH23	UBR3	ENSOARP00000007171	ENSOARP00000002983	Cadherin related 23.	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	0.630
CDH23	USH2A	ENSOARP00000007171	ENSOARP00000011524	Cadherin related 23.	Usherin.	0.834
CUL5	UBR3	ENSOARP00000011663	ENSOARP00000002983	Cullin 5; Belongs to the cullin family.	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	0.808
HECTD1	UBR3	ENSOARP00000006466	ENSOARP00000002983	HECT domain E3 ubiquitin protein ligase 1.	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	0.828
NINL	CDH23	ENSOARP00000002658	ENSOARP00000007171	Uncharacterized protein.	Cadherin related 23.	0.584
NINL	UBR3	ENSOARP00000002658	ENSOARP00000002983	Uncharacterized protein.	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	0.822
NINL	USH2A	ENSOARP00000002658	ENSOARP00000011524	Uncharacterized protein.	Usherin.	0.660
SHISA2	UBR3	ENSOARP00000018286	ENSOARP00000002983	Shisa family member 2.	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	0.600
SHISA2	WDTC1	ENSOARP00000018286	ENSOARP00000003935	Shisa family member 2.	WD and tetratricopeptide repeats 1.	0.578
UBR3	ARHGAP4	ENSOARP00000002983	ENSOARP00000001579	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	Rho GTPase activating protein 4.	0.710
UBR3	CDH23	ENSOARP00000002983	ENSOARP00000007171	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	Cadherin related 23.	0.630
UBR3	CUL5	ENSOARP00000002983	ENSOARP00000011663	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	Cullin 5; Belongs to the cullin family.	0.808
UBR3	HECTD1	ENSOARP00000002983	ENSOARP00000006466	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	HECT domain E3 ubiquitin protein ligase 1.	0.828
UBR3	NINL	ENSOARP00000002983	ENSOARP00000002658	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	Uncharacterized protein.	0.822
UBR3	SHISA2	ENSOARP00000002983	ENSOARP00000018286	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	Shisa family member 2.	0.600
UBR3	UBR5	ENSOARP00000002983	ENSOARP00000018851	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	Ubiquitin protein ligase E3 component n-recognin 5.	0.568
UBR3	UBR7	ENSOARP00000002983	ENSOARP00000014511	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	UBR-type domain-containing protein.	0.579
UBR3	USH2A	ENSOARP00000002983	ENSOARP00000011524	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	Usherin.	0.659

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