close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCDC117Coiled-coil domain containing 117. (278 aa)    
Predicted Functional Partners:
VEPH1
Ventricular zone expressed PH domain containing 1.
      
 0.907
MEGF11
Multiple EGF like domains 11.
      
 0.891
CNTNAP5
Contactin associated protein like 5.
      
 0.889
SLC16A4
Solute carrier family 16 member 4.
      
 0.869
GYPC
4.1m domain-containing protein.
      
 0.828
PTAFR
Platelet activating factor receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.813
MSANTD4
Myb/SANT DNA binding domain containing 4 with coiled-coils.
      
 0.810
PIK3R5
Phosphoinositide-3-kinase regulatory subunit 5.
      
 0.677
SSH2
Slingshot protein phosphatase 2.
      
 0.657
PBRM1
Polybromo 1.
      
 0.655
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.