STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHH3Pleckstrin homology, MyTH4 and FERM domain containing H3. (775 aa)    
Predicted Functional Partners:
WHRN
Whirlin.
    
 0.613
USH1G
USH1 protein network component sans.
   
 0.594
ANKS4B
Ankyrin repeat and sterile alpha motif domain containing 4B.
   
 0.594
USH1C
USH1 protein network component harmonin.
   
 0.585
PLEKHA2
Pleckstrin homology domain containing A2.
      
 0.536
PLEKHG1
Pleckstrin homology and RhoGEF domain containing G1.
      
 0.531
CNIH1
Cornichon family AMPA receptor auxiliary protein 1.
      
 0.510
CASS4
Cas scaffold protein family member 4.
    
 0.499
KCNH4
Potassium voltage-gated channel subfamily H member 4.
   
  
 0.495
W5PBG8_SHEEP
Uncharacterized protein.
   
  
 0.487
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.