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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PSTPIP2Proline-serine-threonine phosphatase interacting protein 2. (337 aa)    
Predicted Functional Partners:
ITSN2
Intersectin 2.
   
 0.952
ITSN1
Intersectin 1.
   
 0.866
RNF165
Ring finger protein 165.
      
 0.814
LAIR1
Ig-like domain-containing protein.
   
    0.780
ATP5F1A
ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
    
 0.767
LOXHD1
Lipoxygenase homology domains 1.
    
 
 0.729
HAUS1
HAUS augmin like complex subunit 1.
      
 0.720
EPG5
Ectopic P-granules autophagy protein 5 homolog.
 
    
 0.701
TTBK2
Tau tubulin kinase 2.
   
 
 0.670
AP2S1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
 0.669
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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