Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SLC45A4Solute carrier family 45 member 4. (778 aa)    
Predicted Functional Partners:
EPS8L3
EPS8 like 3.
      
 0.750
SUSD5
Sushi domain containing 5.
      
 0.696
SRARP
Steroid receptor associated and regulated protein.
      
 0.671
SLC31A1
Solute carrier family 31 member 1.
      
 0.660
FRMPD3
FERM and PDZ domain containing 3.
   
  
 0.644
SULT1C3
Sulfotransferase; Belongs to the sulfotransferase 1 family.
   
  
 0.632
VXN
DUF4648 domain-containing protein.
      
 0.631
ZDHHC22
Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.
      
 0.629
KCNG2
Potassium voltage-gated channel modifier subfamily G member 2; Belongs to the potassium channel family.
      
 0.629
OTOGL
Otogelin like.
      
 0.620
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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