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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLC45A4Solute carrier family 45 member 4. (778 aa)    
Predicted Functional Partners:
EPS8L3
EPS8 like 3.
      
 0.828
NUP210L
Nucleoporin 210 like.
      
 0.700
W5Q5L3_SHEEP
Uncharacterized protein.
      
 0.692
SLC6A19
Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
      
 0.660
KANSL1L
KAT8 regulatory NSL complex subunit 1 like.
      
 0.589
COL18A1
Collagen type XVIII alpha 1 chain.
      
 0.582
W5NV18_SHEEP
Uncharacterized protein.
      
 0.576
ZSWIM4
Zinc finger SWIM-type containing 4.
   
  
 0.544
ATXN2L
Ataxin 2 like.
      
 0.540
SLC31A1
Solute carrier family 31 member 1.
      
 0.538
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.