STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RTN4Reticulon. (1198 aa)    
Predicted Functional Partners:
RTN3
Reticulon.
    
0.967
BACE1
Beta-secretase 1; Belongs to the peptidase A1 family.
   
 0.954
BACE2
Beta-secretase 2; Belongs to the peptidase A1 family.
   
 0.927
ATL3
Atlastin GTPase 3.
    
 
 0.782
OMG
Oligodendrocyte myelin glycoprotein.
    
 0.773
ATL1
Atlastin GTPase 1.
    
 
 0.758
LINGO1
Leucine rich repeat and Ig domain containing 1.
   
 0.743
ATL2
Atlastin GTPase 2.
    
 
 0.737
MAG
Myelin associated glycoprotein.
   
 
 0.736
NGFR
Nerve growth factor receptor.
     
 0.732
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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