close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RBFOX3RNA binding protein fox-1 homolog 3; RNA-binding protein that regulates alternative splicing events. (386 aa)    
Predicted Functional Partners:
CELF3
CUGBP Elav-like family member 3.
  
  
 0.762
PTBP2
Polypyrimidine tract binding protein 2.
    
 0.687
SRRM4
Serine/arginine repetitive matrix 4.
   
 
 0.634
GFAP
Glial fibrillary acidic protein; Belongs to the intermediate filament family.
   
 0.633
MEX3B
Mex-3 RNA binding family member B.
    
 
 0.633
SLC1A3
Amino acid transporter.
   
  
 0.616
ALDH1L1
Aldehyde dehydrogenase 1 family member L1; Belongs to the aldehyde dehydrogenase family.
      
 0.614
W5QC75_SHEEP
Uncharacterized protein.
  
  
 0.603
SRRM3
Serine/arginine repetitive matrix 3.
   
 
 0.599
ELAVL2
ELAV-like protein; Belongs to the RRM elav family.
  
 0.590
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.