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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSOARP00000003109annotation not available (72 aa)    
Predicted Functional Partners:
HMGA1
High mobility group AT-hook 1.
   
 
 0.734
IGF2BP2
Insulin like growth factor 2 mRNA binding protein 2.
   
 
 0.723
NCAPG
Non-SMC condensin I complex subunit G.
      
 0.613
ZFAT
Zinc finger and AT-hook domain containing.
      
 0.613
IGF2BP3
Insulin like growth factor 2 mRNA binding protein 3.
   
 
 0.605
LIN28B
Lin-28 homolog B.
      
 0.589
CTNNB1
Catenin beta 1.
    
 
 0.580
SUOX
Sulfite oxidase.
      
 0.572
LASP1
LIM and SH3 protein 1.
      
 0.570
MSRB3
Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.
      
 0.567
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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