RCC1 protein (Ovis aries) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

RCC1

Regulator of chromosome condensation 1. (422 aa)

Predicted Functional Partners:

RAN

0.994

RANGAP1

0.924

ADGRD1

0.918

RANBP1

0.906

RANBP2

0.894

KPNA4

0.869

RABIF

0.864

RANBP3

0.816

KPNA3

0.802

RPGRIP1

0.760

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADGRD1	KPNA3	ENSOARP00000016020	ENSOARP00000009249	Adhesion G protein-coupled receptor D1; Belongs to the G-protein coupled receptor 2 family.	Importin subunit alpha; Functions in nuclear protein import.	0.419
ADGRD1	KPNA4	ENSOARP00000016020	ENSOARP00000002084	Adhesion G protein-coupled receptor D1; Belongs to the G-protein coupled receptor 2 family.	Importin subunit alpha; Functions in nuclear protein import.	0.419
ADGRD1	RANBP1	ENSOARP00000016020	ENSOARP00000019660	Adhesion G protein-coupled receptor D1; Belongs to the G-protein coupled receptor 2 family.	RAN binding protein 1.	0.908
ADGRD1	RANBP2	ENSOARP00000016020	ENSOARP00000000590	Adhesion G protein-coupled receptor D1; Belongs to the G-protein coupled receptor 2 family.	RAN binding protein 2.	0.939
ADGRD1	RANGAP1	ENSOARP00000016020	ENSOARP00000019475	Adhesion G protein-coupled receptor D1; Belongs to the G-protein coupled receptor 2 family.	Ran GTPase activating protein 1.	0.886
ADGRD1	RCC1	ENSOARP00000016020	ENSOARP00000003127	Adhesion G protein-coupled receptor D1; Belongs to the G-protein coupled receptor 2 family.	Regulator of chromosome condensation 1.	0.918
KPNA3	ADGRD1	ENSOARP00000009249	ENSOARP00000016020	Importin subunit alpha; Functions in nuclear protein import.	Adhesion G protein-coupled receptor D1; Belongs to the G-protein coupled receptor 2 family.	0.419
KPNA3	KPNA4	ENSOARP00000009249	ENSOARP00000002084	Importin subunit alpha; Functions in nuclear protein import.	Importin subunit alpha; Functions in nuclear protein import.	0.965
KPNA3	RAN	ENSOARP00000009249	ENSOARP00000016488	Importin subunit alpha; Functions in nuclear protein import.	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	0.419
KPNA3	RANBP1	ENSOARP00000009249	ENSOARP00000019660	Importin subunit alpha; Functions in nuclear protein import.	RAN binding protein 1.	0.767
KPNA3	RANBP2	ENSOARP00000009249	ENSOARP00000000590	Importin subunit alpha; Functions in nuclear protein import.	RAN binding protein 2.	0.690
KPNA3	RANBP3	ENSOARP00000009249	ENSOARP00000007163	Importin subunit alpha; Functions in nuclear protein import.	RAN binding protein 3.	0.694
KPNA3	RCC1	ENSOARP00000009249	ENSOARP00000003127	Importin subunit alpha; Functions in nuclear protein import.	Regulator of chromosome condensation 1.	0.802
KPNA4	ADGRD1	ENSOARP00000002084	ENSOARP00000016020	Importin subunit alpha; Functions in nuclear protein import.	Adhesion G protein-coupled receptor D1; Belongs to the G-protein coupled receptor 2 family.	0.419
KPNA4	KPNA3	ENSOARP00000002084	ENSOARP00000009249	Importin subunit alpha; Functions in nuclear protein import.	Importin subunit alpha; Functions in nuclear protein import.	0.965
KPNA4	RAN	ENSOARP00000002084	ENSOARP00000016488	Importin subunit alpha; Functions in nuclear protein import.	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	0.422
KPNA4	RANBP1	ENSOARP00000002084	ENSOARP00000019660	Importin subunit alpha; Functions in nuclear protein import.	RAN binding protein 1.	0.605
KPNA4	RANBP2	ENSOARP00000002084	ENSOARP00000000590	Importin subunit alpha; Functions in nuclear protein import.	RAN binding protein 2.	0.690
KPNA4	RANBP3	ENSOARP00000002084	ENSOARP00000007163	Importin subunit alpha; Functions in nuclear protein import.	RAN binding protein 3.	0.768
KPNA4	RCC1	ENSOARP00000002084	ENSOARP00000003127	Importin subunit alpha; Functions in nuclear protein import.	Regulator of chromosome condensation 1.	0.869