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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMIM4Small integral membrane protein 4. (80 aa)    
Predicted Functional Partners:
NGRN
Neugrin, neurite outgrowth associated.
      
 0.613
OCIAD1
OCIA domain containing 1.
      
 0.612
ZNF22
Zinc finger protein 22.
      
 0.591
MALSU1
Mitochondrial assembly of ribosomal large subunit 1.
      
 0.587
DDX28
DEAD-box helicase 28.
      
 0.584
TIMMDC1
Translocase of inner mitochondrial membrane domain containing 1.
      
 0.584
MRM3
Mitochondrial rRNA methyltransferase 3.
      
 0.577
MTERF4
Mitochondrial transcription termination factor 4.
      
 0.573
NSUN4
NOP2/Sun RNA methyltransferase 4; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
      
 0.572
TMEM223
Transmembrane protein 223.
   
  
 0.551
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.