W5NY98_SHEEP protein (Ovis aries) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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[Homology]

Score

W5NY98_SHEEP

Uncharacterized protein. (186 aa)

Predicted Functional Partners:

VCP

0.879

DERL1

0.789

DERL2

0.661

W5PHQ5_SHEEP

0.613

YIF1A

0.586

YIF1B

0.586

SELENOF

0.584

SELENOK

0.574

SELENON

0.546

W5P8I4_SHEEP

0.533

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DERL1	DERL2	ENSOARP00000011741	ENSOARP00000003322	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.994
DERL1	VCP	ENSOARP00000011741	ENSOARP00000013073	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Valosin containing protein; Belongs to the AAA ATPase family.	0.988
DERL1	W5NY98_SHEEP	ENSOARP00000011741	ENSOARP00000003146	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Uncharacterized protein.	0.789
DERL2	DERL1	ENSOARP00000003322	ENSOARP00000011741	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.994
DERL2	SELENOK	ENSOARP00000003322	ENSOARP00000016898	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Selenoprotein K.	0.688
DERL2	VCP	ENSOARP00000003322	ENSOARP00000013073	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Valosin containing protein; Belongs to the AAA ATPase family.	0.954
DERL2	W5NY98_SHEEP	ENSOARP00000003322	ENSOARP00000003146	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Uncharacterized protein.	0.661
SELENOF	SELENOK	ENSOARP00000015977	ENSOARP00000016898	Selenoprotein F.	Selenoprotein K.	0.944
SELENOF	SELENON	ENSOARP00000015977	ENSOARP00000006308	Selenoprotein F.	Selenoprotein N.	0.825
SELENOF	W5NY98_SHEEP	ENSOARP00000015977	ENSOARP00000003146	Selenoprotein F.	Uncharacterized protein.	0.584
SELENOF	W5P8I4_SHEEP	ENSOARP00000015977	ENSOARP00000006739	Selenoprotein F.	Uncharacterized protein.	0.613
SELENOF	W5PHQ5_SHEEP	ENSOARP00000015977	ENSOARP00000009972	Selenoprotein F.	Sep15_SelM domain-containing protein.	0.715
SELENOK	DERL2	ENSOARP00000016898	ENSOARP00000003322	Selenoprotein K.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.688
SELENOK	SELENOF	ENSOARP00000016898	ENSOARP00000015977	Selenoprotein K.	Selenoprotein F.	0.944
SELENOK	SELENON	ENSOARP00000016898	ENSOARP00000006308	Selenoprotein K.	Selenoprotein N.	0.941
SELENOK	VCP	ENSOARP00000016898	ENSOARP00000013073	Selenoprotein K.	Valosin containing protein; Belongs to the AAA ATPase family.	0.542
SELENOK	W5NY98_SHEEP	ENSOARP00000016898	ENSOARP00000003146	Selenoprotein K.	Uncharacterized protein.	0.574
SELENOK	W5P8I4_SHEEP	ENSOARP00000016898	ENSOARP00000006739	Selenoprotein K.	Uncharacterized protein.	0.536
SELENOK	W5PHQ5_SHEEP	ENSOARP00000016898	ENSOARP00000009972	Selenoprotein K.	Sep15_SelM domain-containing protein.	0.690
SELENON	SELENOF	ENSOARP00000006308	ENSOARP00000015977	Selenoprotein N.	Selenoprotein F.	0.825