W5NYC3_SHEEP protein (Ovis aries) - STRING interaction network

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Predicted Interactions

gene neighborhood

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protein homology

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Score

W5NYC3_SHEEP

Uncharacterized protein. (189 aa)

Predicted Functional Partners:

W5NVT1_SHEEP

0.950

ATP2B4

0.948

W5NVU9_SHEEP

0.943

W5Q3L8_SHEEP

0.818

NOS1

0.711

PLN

0.696

TNNI3

0.551

ATP2C1

0.497

ATP2A3

0.492

ATP2A1

0.490

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP2A1	ATP2A3	ENSOARP00000002261	ENSOARP00000019303	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.904
ATP2A1	ATP2B4	ENSOARP00000002261	ENSOARP00000009555	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Uncharacterized protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	0.483
ATP2A1	PLN	ENSOARP00000002261	ENSOARP00000021441	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN.	0.984
ATP2A1	W5NVT1_SHEEP	ENSOARP00000002261	ENSOARP00000002277	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Cation_ATPase_C domain-containing protein.	0.462
ATP2A1	W5NVU9_SHEEP	ENSOARP00000002261	ENSOARP00000002295	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Uncharacterized protein.	0.463
ATP2A1	W5NYC3_SHEEP	ENSOARP00000002261	ENSOARP00000003171	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Uncharacterized protein.	0.490
ATP2A1	W5Q3L8_SHEEP	ENSOARP00000002261	ENSOARP00000017307	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Uncharacterized protein.	0.478
ATP2A3	ATP2A1	ENSOARP00000019303	ENSOARP00000002261	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.904
ATP2A3	ATP2B4	ENSOARP00000019303	ENSOARP00000009555	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Uncharacterized protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	0.484
ATP2A3	PLN	ENSOARP00000019303	ENSOARP00000021441	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN.	0.976
ATP2A3	W5NVT1_SHEEP	ENSOARP00000019303	ENSOARP00000002277	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Cation_ATPase_C domain-containing protein.	0.461
ATP2A3	W5NVU9_SHEEP	ENSOARP00000019303	ENSOARP00000002295	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Uncharacterized protein.	0.466
ATP2A3	W5NYC3_SHEEP	ENSOARP00000019303	ENSOARP00000003171	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Uncharacterized protein.	0.492
ATP2A3	W5Q3L8_SHEEP	ENSOARP00000019303	ENSOARP00000017307	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Uncharacterized protein.	0.474
ATP2B4	ATP2A1	ENSOARP00000009555	ENSOARP00000002261	Uncharacterized protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.483
ATP2B4	ATP2A3	ENSOARP00000009555	ENSOARP00000019303	Uncharacterized protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.484
ATP2B4	ATP2C1	ENSOARP00000009555	ENSOARP00000010107	Uncharacterized protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.472
ATP2B4	NOS1	ENSOARP00000009555	ENSOARP00000004517	Uncharacterized protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	Nitric oxide synthase, brain; Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR (By similarity); Belongs to the NOS family.	0.711
ATP2B4	PLN	ENSOARP00000009555	ENSOARP00000021441	Uncharacterized protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN.	0.696
ATP2B4	TNNI3	ENSOARP00000009555	ENSOARP00000001898	Uncharacterized protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	Troponin I3, cardiac type.	0.551