CLN3 protein (Ovis aries) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Score

CLN3

Battenin. (438 aa)

Predicted Functional Partners:

CLN5

0.949

CLN6

0.938

PPT1

0.907

MFSD8

0.892

TPP1

0.858

CTSD

0.836

KCNIP3

0.789

ABI3BP

0.784

AP5B1

0.781

CTSF

0.764

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABI3BP	AP5B1	ENSOARP00000019535	ENSOARP00000019127	ABI family member 3 binding protein.	Adaptor related protein complex 5 subunit beta 1.	0.852
ABI3BP	CLN3	ENSOARP00000019535	ENSOARP00000003189	ABI family member 3 binding protein.	Battenin.	0.784
AP5B1	ABI3BP	ENSOARP00000019127	ENSOARP00000019535	Adaptor related protein complex 5 subunit beta 1.	ABI family member 3 binding protein.	0.852
AP5B1	CLN3	ENSOARP00000019127	ENSOARP00000003189	Adaptor related protein complex 5 subunit beta 1.	Battenin.	0.781
CLN3	ABI3BP	ENSOARP00000003189	ENSOARP00000019535	Battenin.	ABI family member 3 binding protein.	0.784
CLN3	AP5B1	ENSOARP00000003189	ENSOARP00000019127	Battenin.	Adaptor related protein complex 5 subunit beta 1.	0.781
CLN3	CLN5	ENSOARP00000003189	ENSOARP00000017190	Battenin.	Ceroid-lipofuscinosis neuronal protein 5, secreted form; Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane; Belongs to the CLN5 family.	0.949
CLN3	CLN6	ENSOARP00000003189	ENSOARP00000019771	Battenin.	Uncharacterized protein.	0.938
CLN3	CTSD	ENSOARP00000003189	ENSOARP00000004202	Battenin.	Cathepsin D; Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation.	0.836
CLN3	CTSF	ENSOARP00000003189	ENSOARP00000007726	Battenin.	Cathepsin F; Belongs to the peptidase C1 family.	0.764
CLN3	KCNIP3	ENSOARP00000003189	ENSOARP00000015107	Battenin.	Potassium voltage-gated channel interacting protein 3.	0.789
CLN3	MFSD8	ENSOARP00000003189	ENSOARP00000016738	Battenin.	Major facilitator superfamily domain containing 8.	0.892
CLN3	PPT1	ENSOARP00000003189	ENSOARP00000021672	Battenin.	Palmitoyl-protein thioesterase 1.	0.907
CLN3	TPP1	ENSOARP00000003189	ENSOARP00000018226	Battenin.	Tripeptidyl peptidase 1.	0.858
CLN5	CLN3	ENSOARP00000017190	ENSOARP00000003189	Ceroid-lipofuscinosis neuronal protein 5, secreted form; Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane; Belongs to the CLN5 family.	Battenin.	0.949
CLN5	CLN6	ENSOARP00000017190	ENSOARP00000019771	Ceroid-lipofuscinosis neuronal protein 5, secreted form; Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane; Belongs to the CLN5 family.	Uncharacterized protein.	0.956
CLN5	CTSD	ENSOARP00000017190	ENSOARP00000004202	Ceroid-lipofuscinosis neuronal protein 5, secreted form; Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane; Belongs to the CLN5 family.	Cathepsin D; Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation.	0.906
CLN5	CTSF	ENSOARP00000017190	ENSOARP00000007726	Ceroid-lipofuscinosis neuronal protein 5, secreted form; Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane; Belongs to the CLN5 family.	Cathepsin F; Belongs to the peptidase C1 family.	0.801
CLN5	KCNIP3	ENSOARP00000017190	ENSOARP00000015107	Ceroid-lipofuscinosis neuronal protein 5, secreted form; Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane; Belongs to the CLN5 family.	Potassium voltage-gated channel interacting protein 3.	0.451
CLN5	MFSD8	ENSOARP00000017190	ENSOARP00000016738	Ceroid-lipofuscinosis neuronal protein 5, secreted form; Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane; Belongs to the CLN5 family.	Major facilitator superfamily domain containing 8.	0.874