Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FAM71F1Family with sequence similarity 71 member F1. (343 aa)    
Predicted Functional Partners:
RAB2A
RAB2A, member RAS oncogene family.
   
 0.511
RAB2B
RAB2B, member RAS oncogene family.
   
 0.511
TMCO2
Transmembrane and coiled-coil domains 2.
  
   
 0.498
TNP1
Spermatid nuclear transition protein 1; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction.
  
   
 0.478
ODF1
Outer dense fiber of sperm tails 1.
  
   
 0.462
TNC
Tenascin C.
   
  0.453
TNR
Tenascin R.
   
  0.453
TNN
Tenascin N.
    
  0.446
C11orf42
Chromosome 11 open reading frame 42.
  
     0.428
IQCF1
IQ motif containing F1.
  
   
 0.426
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
Server load: medium (52%) [HD]