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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM71F1Family with sequence similarity 71 member F1. (343 aa)    
Predicted Functional Partners:
ODF1
Outer dense fiber of sperm tails 1.
  
   
 0.621
TMCO2
Transmembrane and coiled-coil domains 2.
  
   
 0.614
TNP1
Spermatid nuclear transition protein 1; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction.
  
   
 0.590
W5P3A5_SHEEP
Uncharacterized protein.
   
 
 0.561
ANKRD9
Uncharacterized protein.
    
 0.541
TTLL2
Tubulin tyrosine ligase like 2.
    
 
 0.538
CCDC54
Coiled-coil domain containing 54.
      
 0.536
CFAP206
Uncharacterized protein.
    
 0.529
FAM81B
Family with sequence similarity 81 member B.
      
 0.529
CT83
Cancer/testis antigen 83.
      
 0.529
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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