STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CEP135Centrosomal protein 135. (1139 aa)    
Predicted Functional Partners:
ITSN2
Intersectin 2.
   
 0.990
PLK4
Polo like kinase 4.
   
 0.975
PLK1
Serine/threonine-protein kinase PLK.
   
 0.959
CETN1
Centrin 1.
    
 
 0.958
CENPJ
Centromere protein J.
   
 
 0.932
POC1B
POC1 centriolar protein B.
    
 
 0.922
ITSN1
Intersectin 1.
   
 0.916
LRRC45
Leucine rich repeat containing 45.
      
 0.903
POC5
POC5 centriolar protein.
      
 0.897
WDR62
WD repeat domain 62.
      
 0.867
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.