PLEKHG1 protein (Ovis aries) - STRING interaction network

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Predicted Interactions

gene neighborhood

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[Homology]

Score

PLEKHG1

Pleckstrin homology and RhoGEF domain containing G1. (1366 aa)

Predicted Functional Partners:

HACD3

0.887

ZBTB1

0.828

ZNF131

0.763

ZBTB33

0.763

STK32A

0.714

DYNC1LI2

0.687

GPR149

0.657

ZNF175

0.639

B3GNT4

0.618

GULP1

0.613

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B3GNT4	HACD3	ENSOARP00000004955	ENSOARP00000019282	Hexosyltransferase.	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	0.482
B3GNT4	PLEKHG1	ENSOARP00000004955	ENSOARP00000003209	Hexosyltransferase.	Pleckstrin homology and RhoGEF domain containing G1.	0.618
B3GNT4	ZBTB1	ENSOARP00000004955	ENSOARP00000001040	Hexosyltransferase.	Zinc finger and BTB domain containing 1.	0.431
B3GNT4	ZNF175	ENSOARP00000004955	ENSOARP00000015833	Hexosyltransferase.	Zinc finger protein 175.	0.828
DYNC1LI2	PLEKHG1	ENSOARP00000002268	ENSOARP00000003209	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	Pleckstrin homology and RhoGEF domain containing G1.	0.687
GPR149	GULP1	ENSOARP00000003684	ENSOARP00000017730	G protein-coupled receptor 149.	GULP PTB domain containing engulfment adaptor 1.	0.600
GPR149	PLEKHG1	ENSOARP00000003684	ENSOARP00000003209	G protein-coupled receptor 149.	Pleckstrin homology and RhoGEF domain containing G1.	0.657
GPR149	STK32A	ENSOARP00000003684	ENSOARP00000003651	G protein-coupled receptor 149.	Serine/threonine kinase 32A; Belongs to the protein kinase superfamily.	0.716
GULP1	GPR149	ENSOARP00000017730	ENSOARP00000003684	GULP PTB domain containing engulfment adaptor 1.	G protein-coupled receptor 149.	0.600
GULP1	PLEKHG1	ENSOARP00000017730	ENSOARP00000003209	GULP PTB domain containing engulfment adaptor 1.	Pleckstrin homology and RhoGEF domain containing G1.	0.613
GULP1	STK32A	ENSOARP00000017730	ENSOARP00000003651	GULP PTB domain containing engulfment adaptor 1.	Serine/threonine kinase 32A; Belongs to the protein kinase superfamily.	0.694
HACD3	B3GNT4	ENSOARP00000019282	ENSOARP00000004955	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	Hexosyltransferase.	0.482
HACD3	PLEKHG1	ENSOARP00000019282	ENSOARP00000003209	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	Pleckstrin homology and RhoGEF domain containing G1.	0.887
HACD3	ZBTB1	ENSOARP00000019282	ENSOARP00000001040	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	Zinc finger and BTB domain containing 1.	0.742
HACD3	ZBTB33	ENSOARP00000019282	ENSOARP00000013919	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	Zinc finger and BTB domain containing 33.	0.644
HACD3	ZNF131	ENSOARP00000019282	ENSOARP00000009370	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	Zinc finger protein 131.	0.694
HACD3	ZNF175	ENSOARP00000019282	ENSOARP00000015833	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	Zinc finger protein 175.	0.542
PLEKHG1	B3GNT4	ENSOARP00000003209	ENSOARP00000004955	Pleckstrin homology and RhoGEF domain containing G1.	Hexosyltransferase.	0.618
PLEKHG1	DYNC1LI2	ENSOARP00000003209	ENSOARP00000002268	Pleckstrin homology and RhoGEF domain containing G1.	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	0.687
PLEKHG1	GPR149	ENSOARP00000003209	ENSOARP00000003684	Pleckstrin homology and RhoGEF domain containing G1.	G protein-coupled receptor 149.	0.657