STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PMVKPhosphomevalonate kinase. (192 aa)    
Predicted Functional Partners:
MVD
Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.
   
 
 0.987
IDI1
Isopentenyl-diphosphate delta isomerase 1.
   
 
 0.854
MVK
Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
   
 
 0.846
EBP
EXPERA domain-containing protein.
   
  
 0.759
TRAF3IP3
TRAF3 interacting protein 3.
    
 0.732
LSS
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
   
  
 0.705
SQLE
Squalene epoxidase.
   
  
 0.703
FDFT1
Uncharacterized protein.
   
  
 0.699
W5Q6S9_SHEEP
Uncharacterized protein; Belongs to the FPP/GGPP synthase family.
   
 
 0.690
TM7SF2
Transmembrane 7 superfamily member 2.
   
 
 0.686
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.