STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STK3Serine/threonine kinase 3. (494 aa)    
Predicted Functional Partners:
SAV1
Salvador family WW domain containing protein 1.
    
 0.996
MOB1A
MOB kinase activator 1A.
   
 0.990
LATS1
Uncharacterized protein.
    
0.979
CASP3
Caspase 3; Belongs to the peptidase C14A family.
   
 0.975
MOB1B
MOB kinase activator 1B.
    
 0.964
RASSF1
Uncharacterized protein.
    
 0.963
RASSF2
Ras association domain family member 2.
    
 0.955
RASSF6
Ras association domain family member 6.
    
 0.954
PPP2CB
Serine/threonine-protein phosphatase.
    
 0.921
PPP2R1B
Protein phosphatase 2 scaffold subunit Abeta.
    
 0.905
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.