STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RTN3Reticulon. (1028 aa)    
Predicted Functional Partners:
RTN4
Reticulon.
    
0.967
BACE1
Beta-secretase 1; Belongs to the peptidase A1 family.
   
 0.957
BACE2
Beta-secretase 2; Belongs to the peptidase A1 family.
   
 0.930
ATL3
Atlastin GTPase 3.
    
 
 0.829
ATL1
Atlastin GTPase 1.
    
 
 0.815
REEP2
Receptor expression-enhancing protein.
   
 
 0.771
ATL2
Atlastin GTPase 2.
    
 
 0.754
REEP1
Receptor expression-enhancing protein.
   
 
 0.731
CCPG1
Cell cycle progression 1.
    
 0.725
SEC62
SEC62 homolog, preprotein translocation factor.
    
 
 0.695
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.