STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAML1Mastermind like transcriptional coactivator 1. (824 aa)    
Predicted Functional Partners:
RBPJ
Recombination signal binding protein for immunoglobulin kappa J region.
   
 0.999
NOTCH1
Notch receptor 1.
   
 0.991
NOTCH2
Notch receptor 2.
   
 0.978
NOTCH3-2
NODP domain-containing protein.
   
 0.977
NOTCH4
Notch receptor 4.
    
 0.965
EP300
E1A binding protein p300.
   
 0.963
MAML2
Uncharacterized protein.
    
0.929
RBPJL
Recombination signal binding protein for immunoglobulin kappa J region like.
   
 0.928
KAT2B
Lysine acetyltransferase 2B.
     
 0.911
KAT2A
Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.
     
 0.911
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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