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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CPLX3Complexin 3. (158 aa)    
Predicted Functional Partners:
NXPH4
Neurexophilin; May be signaling molecules that resemble neuropeptides.
      
 0.903
CPLX4
Complexin 4.
     
 
0.900
CPLX2
Complexin 2.
     
 
0.900
HTR1D
G_PROTEIN_RECEP_F1_2 domain-containing protein.
      
 0.848
INPP4B
Inositol polyphosphate-4-phosphatase type II B.
      
 0.687
MOXD1
Monooxygenase DBH like 1.
      
 0.668
LPAR1
Lysophosphatidic acid receptor 1; Receptor for lysophosphatidic acid (LPA). Plays a role in the reorganization of the actin cytoskeleton, cell migration, differentiation and proliferation, and thereby contributes to the responses to tissue damage and infectious agents. Activates downstream signaling cascades via the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Signaling inhibits adenylyl cyclase activity and decreases cellular cAMP levels. Signaling triggers an increase of cytoplasmic Ca(2+) levels. Activates RALA; this leads to the activation of phospholipase C [...]
      
 0.667
GSG1L
Uncharacterized protein.
      
 0.609
COL23A1
Collagen type XXIII alpha 1 chain.
      
 0.568
CCN2
Uncharacterized protein.
      
 0.565
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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