close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
USH1CUSH1 protein network component harmonin. (552 aa)    
Predicted Functional Partners:
USH1G
USH1 protein network component sans.
    
 0.996
CDH23
Cadherin related 23.
   
 
 0.973
ANKS4B
Ankyrin repeat and sterile alpha motif domain containing 4B.
    
 0.945
MYO7A
Myosin VIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 0.933
ESPN
Espin.
   
 0.923
GRXCR2
Glutaredoxin and cysteine rich domain containing 2.
     
 0.893
MYO7B
Myosin VIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 0.889
GIPC3
GIPC PDZ domain containing family member 3.
   
  
 0.866
PCDH15
Protocadherin related 15.
   
 
 0.863
MYO15A
Myosin XVA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 0.860
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.