Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
USH1CUSH1 protein network component harmonin. (552 aa)    
Predicted Functional Partners:
USH1G
USH1 protein network component sans.
   
 0.998
CDH23
Cadherin related 23.
   
 
 0.976
PCDH15
Protocadherin related 15.
   
 
 0.965
ANKS4B
Ankyrin repeat and sterile alpha motif domain containing 4B.
   
 0.941
MYO7A
Myosin VIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 0.931
GIPC3
GIPC PDZ domain containing family member 3.
   
  
 0.895
ESPN
Espin.
   
 0.888
CDHR2
Cadherin related family member 2.
   
 
 0.877
MYO7B
Myosin VIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 0.873
CDHR5
Cadherin related family member 5.
   
 
 0.866
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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