STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LMAN1LLectin, mannose binding 1 like. (555 aa)    
Predicted Functional Partners:
MCFD2
Multiple coagulation factor deficiency 2.
   
 0.914
W5Q575_SHEEP
GOLD domain-containing protein; Belongs to the EMP24/GP25L family.
   
 0.686
GOSR2
Uncharacterized protein; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.
     
 0.654
SEC13
SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family.
   
 
 0.653
SEC23A
Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.
   
 
 0.646
PREB
Prolactin regulatory element binding.
   
 0.643
STX5
Syntaxin 5; Belongs to the syntaxin family.
    
 0.629
SEC22C
SEC22 homolog C, vesicle trafficking protein; Belongs to the synaptobrevin family.
   
 0.624
SEC22A
SEC22 homolog A, vesicle trafficking protein; Belongs to the synaptobrevin family.
   
 0.624
SEC22B
SEC22 homolog B, vesicle trafficking protein (gene/pseudogene); Belongs to the synaptobrevin family.
   
 0.624
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.