STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NKX6-1Homeobox domain-containing protein. (95 aa)    
Predicted Functional Partners:
NKX2-2
NK2 homeobox 2.
   
  
 0.820
PTF1A
Uncharacterized protein.
      
 0.542
ISL1
ISL LIM homeobox 1.
    
 
 0.541
PAX4
Paired box 4.
    
 
 0.519
FOXA2
Forkhead box A2.
      
 0.509
LHX1
LIM homeobox 1.
    
 
 0.503
NEUROG3
Neurogenin 3.
   
  
 0.503
BTBD17
BTB domain containing 17.
   
  
 0.492
CHGA
Chromogranin A.
      
 0.474
NR5A2
Uncharacterized protein.
      
 0.454
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.