STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTPN21Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1144 aa)    
Predicted Functional Partners:
FBXO42
F-box protein 42.
      
 0.824
FBXO6
F-box protein 6.
      
 0.750
NPL
Uncharacterized protein; Belongs to the DapA family.
    
 
 0.636
SNAP47
Synaptosome associated protein 47.
   
 
 0.628
APLP1
Amyloid beta precursor like protein 1.
    
 
 0.593
MTSS1
MTSS I-BAR domain containing 1.
    
 0.580
ADGRL3
Adhesion G protein-coupled receptor L3; Belongs to the G-protein coupled receptor 2 family.
   
  
 0.573
GRB2
Growth factor receptor bound protein 2.
   
 0.570
WWC1
WW and C2 domain containing 1.
    
 
 0.562
GADD45GIP1
GADD45G interacting protein 1.
      
 0.538
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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