STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NUPR1Nuclear protein 1, transcriptional regulator. (82 aa)    
Predicted Functional Partners:
RHBDD2
Rhomboid domain containing 2.
      
 0.645
TP53INP1
Tumor protein p53 inducible nuclear protein 1.
      
 0.643
OTOP3
Otopetrin 3.
      
 0.595
TCF20
Transcription factor 20.
    
 
 0.595
RENBP
Renin binding protein.
      
 0.589
DUSP22
Dual specificity phosphatase 22.
    
 
 0.565
ANTXR1
ANTXR cell adhesion molecule 1.
    
 
 0.542
PNPLA8
Patatin like phospholipase domain containing 8.
      
 0.541
TRIB3
Tribbles pseudokinase 3.
   
  
 0.538
CHAC1
Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.
   
  
 0.519
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.