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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CHORDC1Cysteine and histidine rich domain containing 1. (311 aa)    
Predicted Functional Partners:
SHC4
SHC adaptor protein 4.
      
 0.911
SRM
Spermidine synthase; Belongs to the spermidine/spermine synthase family.
    
 
 0.828
SUGT1
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone.
   
 
 0.675
AHSA1
Activator of HSP90 ATPase activity 1.
   
 
 0.664
HSP90AA1
Heat shock protein alpha.
   
 
 0.642
HSP90AB1
Heat shock protein 90 alpha family class B member 1.
   
 
 0.626
HSP90B1
Heat shock protein 90 beta family member 1.
   
 
 0.621
POLR3C
RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
      
 0.614
PPP5C
Serine/threonine-protein phosphatase.
   
 
 0.612
NUDT17
Nudix hydrolase 17.
      
 0.612
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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