Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CHORDC1Cysteine and histidine rich domain containing 1. (311 aa)    
Predicted Functional Partners:
SHC4
SHC adaptor protein 4.
      
 0.846
HSPH1
Heat shock protein family H (Hsp110) member 1.
   
 
 0.813
UCHL5
Ubiquitin carboxyl-terminal hydrolase.
   
  
 0.800
TTC4
Tetratricopeptide repeat domain 4.
    
 
 0.797
HSP90AA1
Heat shock protein alpha.
   
 
 0.784
HSP90AB1
Heat shock protein 90 alpha family class B member 1.
   
 
 0.783
SUGT1
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone.
   
 
 0.768
PPP5C
Serine/threonine-protein phosphatase.
   
 
 0.737
EDRF1
Erythroid differentiation regulatory factor 1.
    
   0.731
AHSA1
Activator of HSP90 ATPase activity 1.
   
 
 0.728
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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