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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ATAD3AATPase family AAA domain containing 3A. (573 aa)    
Predicted Functional Partners:
CPNE5
Copine 5.
   
  
 0.870
TMBIM6
Transmembrane BAX inhibitor motif containing 6; Belongs to the BI1 family.
      
 0.846
ECSIT
ECSIT signalling integrator.
   
   0.764
TSPO
Translocator protein; Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism, but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme (By similarity). Was initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides.
      
 0.735
NDUFAF1
NADH:ubiquinone oxidoreductase complex assembly factor 1.
    
   0.733
RBM15
RNA binding motif protein 15.
      
 0.717
SLC25A11
SLC25A11; Belongs to the mitochondrial carrier (TC 2.A.29) family.
   
 
 0.715
FAM210A
Family with sequence similarity 210 member A.
    
 
 0.633
TIMM44
Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family.
   
  
 0.632
SSBP1
Single stranded DNA binding protein 1.
    
 
 0.631
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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