Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ZC3H14Uncharacterized protein. (732 aa)    
Predicted Functional Partners:
ALYREF
Aly/REF export factor.
    
 
 0.748
NCBP3
Nuclear cap binding subunit 3.
   
 
 0.706
NCBP1
Nuclear cap binding protein subunit 1.
   
 
 0.704
PNN
Pinin, desmosome associated protein.
    
 
 0.680
SLC25A38
Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the mitochondrial matrix. Required during erythropoiesis. Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
    
 
 0.661
RAE1
Ribonucleic acid export 1.
    
 
 0.651
POLDIP3
DNA polymerase delta interacting protein 3.
    
 
 0.636
TNPO1
Transportin 1.
    
 
 0.628
TNPO2
Transportin 2.
    
 
 0.628
EIF4A3
Uncharacterized protein; Belongs to the DEAD box helicase family.
    
 
 0.621
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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