SGK2 protein (Ovis aries) - STRING interaction network

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Score

SGK2

Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (367 aa)

Predicted Functional Partners:

PDPK1

0.983

FOXO1

0.928

FOXO3

0.928

SGK3

0.907

SGK1

0.901

MTOR

0.853

MAPKAP1

0.798

W5PT13_SHEEP

0.781

RPTOR

0.732

PROCA1

0.725

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FOXO1	FOXO3	ENSOARP00000006433	ENSOARP00000011521	Fork-head domain-containing protein.	Fork-head domain-containing protein.	0.956
FOXO1	MTOR	ENSOARP00000006433	ENSOARP00000002935	Fork-head domain-containing protein.	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	0.488
FOXO1	SGK1	ENSOARP00000006433	ENSOARP00000015778	Fork-head domain-containing protein.	Non-specific serine/threonine protein kinase.	0.954
FOXO1	SGK2	ENSOARP00000006433	ENSOARP00000003442	Fork-head domain-containing protein.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.928
FOXO1	SGK3	ENSOARP00000006433	ENSOARP00000019128	Fork-head domain-containing protein.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.913
FOXO3	FOXO1	ENSOARP00000011521	ENSOARP00000006433	Fork-head domain-containing protein.	Fork-head domain-containing protein.	0.956
FOXO3	MTOR	ENSOARP00000011521	ENSOARP00000002935	Fork-head domain-containing protein.	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	0.406
FOXO3	PDPK1	ENSOARP00000011521	ENSOARP00000020003	Fork-head domain-containing protein.	3-phosphoinositide dependent protein kinase 1.	0.408
FOXO3	RPTOR	ENSOARP00000011521	ENSOARP00000000495	Fork-head domain-containing protein.	Regulatory associated protein of MTOR complex 1.	0.465
FOXO3	SGK1	ENSOARP00000011521	ENSOARP00000015778	Fork-head domain-containing protein.	Non-specific serine/threonine protein kinase.	0.940
FOXO3	SGK2	ENSOARP00000011521	ENSOARP00000003442	Fork-head domain-containing protein.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.928
FOXO3	SGK3	ENSOARP00000011521	ENSOARP00000019128	Fork-head domain-containing protein.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.912
MAPKAP1	MTOR	ENSOARP00000013645	ENSOARP00000002935	Target of rapamycin complex 2 subunit MAPKAP1; Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the [...]	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	0.996
MAPKAP1	PDPK1	ENSOARP00000013645	ENSOARP00000020003	Target of rapamycin complex 2 subunit MAPKAP1; Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the [...]	3-phosphoinositide dependent protein kinase 1.	0.539
MAPKAP1	RPTOR	ENSOARP00000013645	ENSOARP00000000495	Target of rapamycin complex 2 subunit MAPKAP1; Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the [...]	Regulatory associated protein of MTOR complex 1.	0.739
MAPKAP1	SGK1	ENSOARP00000013645	ENSOARP00000015778	Target of rapamycin complex 2 subunit MAPKAP1; Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the [...]	Non-specific serine/threonine protein kinase.	0.869
MAPKAP1	SGK2	ENSOARP00000013645	ENSOARP00000003442	Target of rapamycin complex 2 subunit MAPKAP1; Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the [...]	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.798
MAPKAP1	SGK3	ENSOARP00000013645	ENSOARP00000019128	Target of rapamycin complex 2 subunit MAPKAP1; Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the [...]	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.779
MTOR	FOXO1	ENSOARP00000002935	ENSOARP00000006433	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	Fork-head domain-containing protein.	0.488
MTOR	FOXO3	ENSOARP00000002935	ENSOARP00000011521	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	Fork-head domain-containing protein.	0.406