STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
THEMIS2CABIT domain-containing protein. (374 aa)    
Predicted Functional Partners:
CHKA
Choline kinase alpha.
      
 0.851
XKR8
XK-related protein.
      
 0.842
SMPDL3B
Sphingomyelin phosphodiesterase acid like 3B.
      
 0.840
PACSIN2
Protein kinase C and casein kinase substrate in neurons 2.
      
 0.811
TCIRG1
V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
   
  
 0.744
PCGF5
Polycomb group ring finger 5.
      
 0.714
BATF2
Basic leucine zipper ATF-like transcription factor 2.
   
  
 0.660
GRB2
Growth factor receptor bound protein 2.
   
 
 0.621
SYTL1
Synaptotagmin like 1.
      
 0.587
NDUFS8
NADH:ubiquinone oxidoreductase core subunit S8.
      
 0.559
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.