STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EZH1Enhancer of zeste 1 polycomb repressive complex 2 subunit. (752 aa)    
Predicted Functional Partners:
SUZ12
SUZ12 polycomb repressive complex 2 subunit.
   
 0.999
EED
Embryonic ectoderm development.
   
 0.997
JARID2
Jumonji and AT-rich interaction domain containing 2.
   
 0.977
AEBP2
AE binding protein 2.
   
 0.972
PHF1
PHD finger protein 1.
   
 0.947
RBBP4
WD_REPEATS_REGION domain-containing protein.
   
 0.945
RBBP7
RB binding protein 7, chromatin remodeling factor.
   
 0.924
PHF19
PHD finger protein 19.
   
 0.912
MTF2
Metal response element binding transcription factor 2.
   
 0.901
KDM6B
Lysine demethylase 6B.
   
 0.872
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
Server load: low (22%) [HD]