STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NFATC3Nuclear factor of activated T cells 3. (1067 aa)    
Predicted Functional Partners:
MAPK8
Mitogen-activated protein kinase.
    
 0.975
PPP3R1
Uncharacterized protein.
    
 0.975
PPP3CB
Serine/threonine-protein phosphatase.
    
 0.973
PPP3CA
Serine/threonine-protein phosphatase.
    
 0.972
MAPK10
Mitogen-activated protein kinase.
    
  0.971
NFATC1
Nuclear factor of activated T cells 1.
   
 
0.961
MAPK9
Mitogen-activated protein kinase.
    
 0.958
MAPK3
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
 
 0.924
SRF
Serum response factor.
     
 0.918
GSK3B
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
 0.918
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.